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1

Molecular imaging strategies for drug discovery and development

Shimon Gross, David Piwnica-Worms

Journal:

Current Opinion in Chemical Biology

Year:

2006

Language:

english

File:

PDF, 395 KB

english, 2006

2

TAT-Bim Induces Extensive Apoptosis in Cancer Cells

Hiroyuki Kashiwagi, Jonathan E. McDunn, Peter S. Goedegebuure, Mary C. Gaffney, Katherine Chang, Kathryn Trinkaus, David Piwnica-Worms, Richard S. Hotchkiss, William G. Hawkins

Journal:

Annals of Surgical Oncology

Year:

2007

Language:

english

File:

PDF, 466 KB

english, 2007

3

Book Review MRI: Central nervous system Edited by Walter Kucharczyk. Approximately 300 pp., illustrated. Philadelphia, J.B. Lippincott/Gower Medical, 1990. $79.50. MRI: Musculoskeletal system Edited by Javier Beltran. Approximately 325 pp., illustrated. Philadelphia, J.B. Lippincott/Gower Medical, 1990. $79.50.

Piwnica-Worms, David, Jolesz, Ferenc

Journal:

Boston Medical and Surgical Journal

Year:

1991

File:

PDF, 421 KB

1991

4

MR Imaging of Septic Sacroiliitis

Klein, Mitchell A., Winalski, Carl S., Wax, Mark R., Piwnica-Worms, David R.

Journal:

Journal of Computer Assisted Tomography

Year:

1991

File:

PDF, 825 KB

1991

5

Spatial and Temporal Confined Photothermolysis of Cancer Cells Mediated by Hollow Gold Nanospheres Targeted to Epidermal Growth Factor Receptors

Ku, Geng, Huang, Qian, Wen, Xiaoxia, Ye, John, Piwnica-Worms, David, Li, Chun

Journal:

Year:

2018

Language:

english

File:

PDF, 9.87 MB

english, 2018

6

Squaraine Rotaxanes: Superior Substitutes for Cy-5 in Molecular Probes for Near-Infrared Fluorescence Cell Imaging

James R. Johnson, Na Fu, Easwaran Arunkumar, W. Matthew Leevy, Seth T. Gammon, David Piwnica-Worms, Bradley D. Smith

Journal:

Angewandte Chemie

Year:

2007

Language:

english

File:

PDF, 203 KB

english, 2007

7

Squaraine Rotaxanes: Superior Substitutes for Cy-5 in Molecular Probes for Near-Infrared Fluorescence Cell Imaging

James R. Johnson, Na Fu, Easwaran Arunkumar, W. Matthew Leevy, Seth T. Gammon, David Piwnica-Worms, Bradley D. Smith

Journal:

Angewandte Chemie International Edition

Year:

2007

Language:

english

File:

PDF, 204 KB

english, 2007

8

Rational design of novel red-shifted BRET pairs: Platforms for real-time single-chain protease biosensors

Seth T. Gammon, Victor M. Villalobos, Mikhail Roshal, Mustapha Samrakandi, David Piwnica-Worms

Journal:

Biotechnology Progress

Year:

2009

Language:

english

File:

PDF, 998 KB

english, 2009

9

ChemInform Abstract: Metal Complexes for Therapy and Diagnosis of Drug Resistance

Vijay Sharma, David Piwnica-Worms

Journal:

Year:

1999

File:

PDF, 25 KB

1999

10

APT102, a novel adpase, cooperates with aspirin to disrupt bone metastasis in mice

Özge Uluçkan, Mark C. Eagleton, Desiree H. Floyd, Elizabeth A. Morgan, Angela C. Hirbe, Matthew Kramer, Nikki Dowland, Julie L. Prior, David Piwnica-Worms, Soon Seog Jeong, Ridong Chen, Katherine Weil

Journal:

Journal of Cellular Biochemistry

Year:

2008

Language:

english

File:

PDF, 667 KB

english, 2008

11

Molecular imaging of gene expression and protein function in vivo with PET and SPECT

Vijay Sharma, Gary D. Luker, David Piwnica-Worms

Journal:

Journal of Magnetic Resonance Imaging

Year:

2002

Language:

english

File:

PDF, 808 KB

english, 2002

12

Superparamagnetic Iron Oxide Hepatic MR Imaging: Efficacy and Safety Using Conventional and Fast Spin-Echo Pulse Sequences

Lawrence H. Schwartz, Steven E. Seltzer, Clare M. C. Tempany, Stuart G. Silverman, David R. Piwnica-Worms, Douglass F. Adams, Lee Herman, Lisa A. Herman, Roshann Hooshmand

Journal:

Journal of Magnetic Resonance Imaging

Year:

1995

Language:

english

File:

PDF, 628 KB

english, 1995

13

Mitochondrial localization and characterization of 99Tc-SESTAMIBI in heart cells by electron probe X-ray microanalysis and 99Tc-NMR spectroscopy

David Piwnica-Worms, James F. Kronauge, Ann LeFurgey, Mark Backus, Daniel Hockett, Peter Ingram, Melvyn Lieberman, B. Leonard Holman, Alun G. Jones, Alan Davison

Journal:

Magnetic Resonance Imaging

Year:

1994

Language:

english

File:

PDF, 3.07 MB

english, 1994

14

Dual-Color Click Beetle Luciferase Heteroprotein Fragment Complementation Assays

Victor Villalobos, Snehal Naik, Monique Bruinsma, Robin S. Dothager, Mei-Hsiu Pan, Mustapha Samrakandi, Britney Moss, Adnan Elhammali, David Piwnica-Worms

Journal:

Chemistry & Biology

Year:

2010

Language:

english

File:

PDF, 1.11 MB

english, 2010

15

Advances in bioluminescence imaging of live animal models

Robin S Dothager, Kelly Flentie, Britney Moss, Mei-Hsiu Pan, Aparna Kesarwala, David Piwnica-Worms

Journal:

Current Opinion in Biotechnology

Year:

2009

Language:

english

File:

PDF, 1.99 MB

english, 2009

16

Synthesis, characterization, and molecular structure of a gallium(III) complex of an amine-phenol ligand with activity against chloroquine-sensitive Plasmodium falciparum strains

Joseph A. Ocheskey, Valery R. Polyakov, Scott E. Harpstrite, Anna Oksman, Daniel E. Goldberg, David Piwnica-Worms, Vijay Sharma

Journal:

Journal of Inorganic Biochemistry

Year:

2003

Language:

english

File:

PDF, 218 KB

english, 2003

17

Interaction of (Na + K + 2 Cl) cotransport and the Na/K pump in cultured chick cardiac myocytes

Shi Liu, Ron Jacob, David Piwnica-Worms, Melvyn Lieberman

Journal:

Molecular and Cellular Biochemistry

Year:

1989

Language:

english

File:

PDF, 292 KB

english, 1989

18

Detection of Adriamycin-induced cardiotoxicity in cultured heart cells with technetium 99m-SESTAMIBI

David Piwnica-Worms, Mary L. Chiu, James F. Kronauge

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1993

Language:

english

File:

PDF, 856 KB

english, 1993

19

Technoreview: Molecular imaging of host–pathogen interactions in intact small animals

David Piwnica-Worms, Daniel P. Schuster, Joel R. Garbow

Journal:

Cellular Microbiology

Year:

2004

Language:

english

File:

PDF, 391 KB

english, 2004

20

Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate

Draetta, Giulio, Piwnica-Worms, Helen, Morrison, Deborah, Druker, Brian, Roberts, Thomas, Beach, David

Journal:

Year:

1988

File:

PDF, 892 KB

1988

21

Bioluminescence imaging of myeloperoxidase activity in vivo

Gross, Shimon, Gammon, Seth T, Moss, Britney L, Rauch, Daniel, Harding, John, Heinecke, Jay W, Ratner, Lee, Piwnica-Worms, David

Journal:

Nature Medicine

Year:

2009

Language:

english

File:

PDF, 648 KB

english, 2009

22

Imaging 26S proteasome activity and inhibition in living mice

Luker, Gary D, Pica, Christina M, Song, Jiling, Luker, Kathryn E, Piwnica-Worms, David

Journal:

Nature Medicine

Year:

2003

Language:

english

File:

PDF, 343 KB

english, 2003

23

Real-time imaging of ligand-induced IKK activation in intact cells and in living mice

Gross, Shimon, Piwnica-Worms, David

Journal:

Year:

2005

Language:

english

File:

PDF, 667 KB

english, 2005

24

Knocking down nucleolin expression in gliomas inhibits tumor growth and induces cell cycle arrest

Zhiqiang Xu, Neel Joshi, Ashima Agarwal, Sonika Dahiya, Patrice Bittner, Erin Smith, Sara Taylor, David Piwnica-Worms, Jason Weber, Jeffrey R. Leonard

Journal:

Journal of Neuro-Oncology

Year:

2012

Language:

english

File:

PDF, 683 KB

english, 2012

25

Spying on cancer: Molecular imaging in vivo with genetically encoded reporters

Shimon Gross, David Piwnica-Worms

Journal:

Year:

2005

Language:

english

File:

PDF, 644 KB

english, 2005

26

Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID β2mnull mice

Bruno Nervi, Michael P. Rettig, Julie K. Ritchey, Hanlin L. Wang, Gerhard Bauer, Jon Walker, Mark L. Bonyhadi, Ronald J. Berenson, Julie L. Prior, David Piwnica-Worms, Jan A. Nolta, John F. DiPersio

Journal:

Experimental Hematology

Year:

2007

Language:

english

File:

PDF, 1.65 MB

english, 2007

27

CXCL12 alone is insufficient for gliomagenesis in Nf1 mutant mice

Tao Sun, Scott M. Gianino, Erin Jackson, David Piwnica-Worms, David H. Gutmann, Joshua B. Rubin

Journal:

Journal of Neuroimmunology

Year:

2010

Language:

english

File:

PDF, 403 KB

english, 2010

28

Effects of MDR1 and MDR3 P-glycoproteins, MRP1, and BCRP/MXR/ABCP on the transport of 99mTc-tetrofosmin

Wendy S. Chen, Kathryn E. Luker, Julie L. Dahlheimer, Christina M. Pica, Gary D. Luker, David Piwnica-Worms

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 416 KB

english, 2000

29

An Improved Cell-Penetrating, Caspase-Activatable, Near-Infrared Fluorescent Peptide for Apoptosis Imaging

Maxwell, Dustin, Chang, Qing, Zhang, Xu, Barnett, Edward M., Piwnica-Worms, David

Journal:

Bioconjugate Chemistry

Year:

2009

Language:

english

File:

PDF, 1.52 MB

english, 2009

30

Ovarian vein thrombosis

Grant R. Simons, David R. Piwnica-Worms, Samuel Z. Goldhaber

Journal:

American Heart Journal

Year:

1993

Language:

english

File:

PDF, 3.17 MB

english, 1993

31

Membrane potential determination in large unilamellar vesicles with hexakis(2-methoxyisobutylisonitrile)technetium(I)

Daniel M. Chernoff, Gary R. Strichartz, David Piwnica-Worms

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1993

Language:

english

File:

PDF, 515 KB

english, 1993

32

The bisphosphonate zoledronic acid decreases tumor growth in bone in mice with defective osteoclasts

Angela C. Hirbe, Anke J. Roelofs, Desiree H. Floyd, Hongju Deng, Stephanie N. Becker, Lisa G. Lanigan, Anthony J. Apicelli, Zhiqiang Xu, Julie L. Prior, Mark C. Eagleton, David Piwnica-Worms, Michael

Journal:

Year:

2009

Language:

english

File:

PDF, 1.51 MB

english, 2009

33

P8. Osteoclast dysfunction in CD47−/− mice suppresses metastatic tumor burden and osteolysis

Ozge Uluckan, Hongju Deng, Julie L. Prior, David Piwnica-Worms, William A. Frazier, Katherine N. Weilbaecher

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 40 KB

english, 2008

34

Granzyme B and Perforin Are Important for Regulatory T Cell-Mediated Suppression of Tumor Clearance

Xuefang Cao, Sheng F. Cai, Todd A. Fehniger, Jiling Song, Lynne I. Collins, David R. Piwnica-Worms, Timothy J. Ley

Journal:

Year:

2007

Language:

english

File:

PDF, 1.69 MB

english, 2007

35

Veni, Vidi, Vici: In Vivo Molecular Imaging of Immune Response

Shimon Gross, Britney L. Moss, David Piwnica-Worms

Journal:

Year:

2007

Language:

english

File:

PDF, 298 KB

english, 2007

36

SPECT metalloprobes for monitoring MDR1 P-glycoprotein-mediated transport at the blood-brain barrier

Jothilingam Sivapackiam, Scott E. Harpstrite, Julie L. Prior, David Piwnica-Worms, Vijay Sharma

Journal:

Nuclear Medicine and Biology

Year:

2010

Language:

english

File:

PDF, 67 KB

english, 2010

37

A Novel Areneisonitrile Tc Complex Inhibits the Transport Activity of MDR P-Glycoprotein

Vallabhaneni V Rao, Lee W Herman, James F Kronauge, David Piwnica-Worms

Journal:

Nuclear Medicine and Biology

Year:

1998

Language:

english

File:

PDF, 979 KB

english, 1998

38

Visualizing protein–protein interactions in living animals

Gary D. Luker, Vijay Sharma, David Piwnica-Worms

Journal:

Year:

2003

Language:

english

File:

PDF, 291 KB

english, 2003

39

Na/H exchange in cultured chick heart cells: Secondary stimulation of electrogenic transport during recovery from intracellular acidosis

David Piwnica-Worms, Ron Jacob, Norikazu Shigeto, C. Russell Horres, Melvyn Lieberman

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1986

Language:

english

File:

PDF, 587 KB

english, 1986

40

Human cord blood progenitors with high aldehyde dehydrogenase activity improve vascular density in a model of acute myocardial infarction

Claus S Sondergaard, David A Hess, Dustin J Maxwell, Carla Weinheimer, Ivana Rosová, Michael H Creer, David Piwnica-Worms, Attila Kovacs, Lene Pedersen, Jan A Nolta

Journal:

Journal of Translational Medicine

Year:

2010

Language:

english

File:

PDF, 1.19 MB

english, 2010

41

T-cell activation promotes tumorigenesis in inflammation-associated cancer

Dan Rauch, Shimon Gross, John Harding, Sirosh Bokhari, Stefan Niewiesk, Michael Lairmore, David Piwnica-Worms, Lee Ratner

Journal:

Year:

2009

Language:

english

File:

PDF, 3.79 MB

english, 2009

42

Fluorophore-Conjugated Iron Oxide Nanoparticle Labeling and Analysis of Engrafting Human Hematopoietic Stem Cells

Dustin J. Maxwell, Jesper Bonde, David A. Hess, Sarah A. Hohm, Ryan Lahey, Ping Zhou, Michael H. Creer, David Piwnica-Worms, Jan A. Nolta

Journal:

Year:

2008

Language:

english

File:

PDF, 1.02 MB

english, 2008

43

Structure–activity relationships, kinetics, selectivity, and mechanistic studies of synthetic hydraphile channels in bacterial and mammalian cells

Leevy, W. Matthew, Gammon, Seth T., Levchenko, Tatiana, Daranciang, David D., Murillo, Oscar, Torchilin, Vladimir, Piwnica-Worms, David, Huettner, James E., Gokel, George W.

Journal:

Organic & Biomolecular Chemistry

Year:

2005

Language:

english

File:

PDF, 269 KB

english, 2005

44

Synthesis and Characterization of a Small, Membrane-Permeant, Caspase-Activatable Far-Red Fluorescent Peptide for Imaging Apoptosis

Bullok, Kristin, Piwnica-Worms, David

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 139 KB

english, 2005

45

The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis

Zhang, Kun, Corsa, Callie A., Ponik, Suzanne M., Prior, Julie L., Piwnica-Worms, David, Eliceiri, Kevin W., Keely, Patricia J., Longmore, Gregory D.

Journal:

Nature Cell Biology

Year:

2013

Language:

english

File:

PDF, 5.38 MB

english, 2013

46

Novel Tat-Peptide Chelates for Direct Transduction of Technetium-99m and Rhenium into Human Cells for Imaging and Radiotherapy

Polyakov, Valery, Sharma, Vijay, Dahlheimer, Julie L., Pica, Christina M., Luker, Gary D., Piwnica-Worms, David

Journal:

Bioconjugate Chemistry

Year:

2000

Language:

english

File:

PDF, 207 KB

english, 2000

47

The Extracellular Domain of Notch2 Increases Its Cell-Surface Abundance and Ligand Responsiveness during Kidney Development

Liu, Zhenyi, Chen, Shuang, Boyle, Scott, Zhu, Yu, Zhang, Andrew, Piwnica-Worms, David R., Ilagan, Ma. Xenia G., Kopan, Raphael

Journal:

Developmental Cell

Year:

2013

Language:

english

File:

PDF, 7.10 MB

english, 2013

48

Characterization of Novel Histidine-Tagged Tat-Peptide Complexes Dual-Labeled with 99m Tc-Tricarbonyl and Fluorescein for Scintigraphy and Fluorescence Microscopy

Bullok, Kristin E., Dyszlewski, Mary, Prior, Julie L., Pica, Christina M., Sharma, Vijay, Piwnica-Worms, David

Journal:

Bioconjugate Chemistry

Year:

2002

Language:

english

File:

PDF, 413 KB

english, 2002

49

Caspase-Activated Cell-Penetrating Peptides Reveal Temporal Coupling Between Endosomal Release and Apoptosis in an RGC-5 Cell Model

Johnson, James R., Kocher, Brandon, Barnett, Edward M., Marasa, Jayne, Piwnica-Worms, David

Journal:

Bioconjugate Chemistry

Year:

2012

Language:

english

File:

PDF, 4.44 MB

english, 2012

50

Current State of Imaging Protein-Protein Interactions In Vivo with Genetically Encoded Reporters

Villalobos, Victor, Naik, Snehal, Piwnica-Worms, David

Journal:

Annual Review of Biomedical Engineering

Year:

2007

Language:

english

File:

PDF, 806 KB

english, 2007

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